Emily Glover

Emily Glover completed her Nuffield Research Placement in 2016 at The University of Manchester. She went on to present her work at The Big Bang Fair.

Why did you apply for a Nuffield Research Placement?

I knew that I definitely wanted to have a career in science and I wanted to see what it would be like to work in a research environment.

What was your project about and did you know anything about the area before you started the placement?

I was investigating whether lentiviral produced human IL-1Ra could reduce IL-1β dependent inflammation in a mouse macrophage cell line, in turn allowing assessment of vector biological activity.  If the vector produced biologically active human IL-1Ra, lentiviral mediated IL-1Ra would be a potential anti-inflammatory therapy for neuro-inflammation in a paediatric disease called Mucopolysaccharidosis (MPS) IIIA.

I didn’t know anything about the subject area before the placement, so my supervisor gave me a couple of relevant papers to look over before it began.

Did you gain any new skills, both scientific and general work skills, from undertaking your placement?

I learnt lots of new practical techniques; cell culture, transductions, ELISAs.  I also learnt how to carry out statistical analysis on my results and wrote up a formal scientific report.

How did your supervisor help you with your project?

My supervisor was amazing; she taught me all the practical skills I needed in the lab, how to interpret my results and proof read my report.

What advice would you give to students applying for a Nuffield Research Placement?

Make sure you get across your enthusiasm for the subject in your application.

What was it like presenting your work at The Big Bang Competition?

It was really fun.  I met loads of other Nuffield students there from across the country and made lots of friends that I’m still in touch with now.